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CHAPTER TWO. Healing Response in Acute and Chronic Wounds

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A contaminated, full thickness wound of significant size would most likely undergo which category(s) of healing?

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a. Category 1 (primary healing)

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b. Category 2 (delayed primary healing)

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c. Category 3 (secondary healing)

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d. Category 4 (chronic wound healing)

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Critical wound healing is the time required for a wound to heal to the point where it becomes self-supportive and function has been restored. T or F?

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a. True

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b. False

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Which wound healing phase is characterized by granulation tissue?

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a. Hemostasis

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b. Inflammation

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c. Proliferation/maturation

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d. Remodeling

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When does inflammation begin?

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a. Immediately post-injury

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b. When neo-angiogenesis is evident in the wound bed

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c. When bleeding is fully arrested

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d. When wound contraction is evident

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When does proliferation begin?

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a. Proliferation overlaps with inflammation with epithelial cell migration at the wound edges.

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b. When the damaged tissue has largely been replaced and begins to regain strength with the deposition of collagen, primarily type III.

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c. When there is an expansion of blood vessels (angiogenesis) and the initiation of wound contraction to complement closure that is driven by the presence of myofibroblasts.

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d. When capillary buds are first visible in the wound bed.

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During remodeling, Type III collagen is replaced with

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a. Type I collagen

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b. Type II collagen

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c. Type IV collagen

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d. Type V collagen

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