PREFERRED PRACTICE PATTERNS4
A 25-year-old female referred with significant sarcopenia and a BMI of 16. Her gait is unstable and she demonstrates coordination deficits. She is mildly short of breath on exertion. She describes little interest in food, but does have self-described craving for potato chips at times. Of late, she is too tired to exercise and she thinks it is because she is depressed. Her history reveals that she menstruates infrequently over the past year and that her skin tone has changed.
Clinical features of Addison disease. Note the hyperpigmentation in areas of increased friction including (A) palmar creases, (B) dorsal foot, (C) nipples and axillary region, and (D) patchy hyperpigmentation of the oral mucosa. (From Longo DL, Fauci A, Kasper D, et al., eds. Harrison’s Principles of Internal Medicine. 18th ed. New York, NY: McGraw-Hill; 2012.)
Insufficient production or release of glucocorticoids (cortisol),1 androgens, and mineralocorticoids from the adrenal glands
These hormones play a role in
Conversion of food to energy
Response to stress
Maintaining sodium–potassium balance for blood pressure regulation and production of androgens in males and women, involved in maintaining libido
May be insidious onset or sudden onset as in Addisonian crisis
May cause pathology in multiple organ systems or be caused by pathology in other organ systems
Confirmation of suspected disease through blood testing
Log In to View More
If you don't have a subscription, please view our individual subscription options below to find out how you can gain access to this content.
Want remote access to your institution's subscription?
Sign in to your MyAccess profile while you are actively authenticated on this site via your institution (you will be able to verify this by looking at the top right corner of the screen - if you see your institution's name, you are authenticated). Once logged in to your MyAccess profile, you will be able to access your institution's subscription for 90 days from any location. You must be logged in while authenticated at least once every 90 days to maintain this remote access.
If your institution subscribes to this resource, and you don't have a MyAccess profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus.
AccessPhysiotherapy Full Site: One-Year Subscription
Connect to the full suite of AccessPhysiotherapy content and resources including interactive NPTE review, more than 500 videos, Anatomy & Physiology Revealed, 20+ leading textbooks, and more.
Pay Per View: Timed Access to all of AccessPhysiotherapy
24 Hour Subscription $34.95
48 Hour Subscription $54.95
Pop-up div Successfully Displayed
This div only appears when the trigger link is hovered over.
Otherwise it is hidden from view.