Skip to Main Content




  • Diffuse thyrotoxic goiter




  • 242.0 Toxic diffuse goiter

  • PT diagnoses codes that may be secondary to thyroid disorders

    • 315.4 Developmental coordination disorder

    • 709.2 Scar conditions and fibrosis of the skin

    • 719.70 Difficulty in walking involving joint site unspecified

    • 728.2 Muscular wasting and disuse atrophy, not elsewhere classified

    • 728.89 Other disorders of muscle, ligament, and fascia

    • 729.9 Other and unspecified disorders of soft tissue

    • 781.2 Abnormality of gait

    • 782.3 Edema

    • 786.0 Dyspnea and respiratory abnormalities

    • 786.05 Shortness of breath




  • E05 Thyrotoxicosis (hyperthyroidism)

  • E05.0 Thyrotoxicosis with diffuse goiter




  • 4D: Impaired Joint Mobility, Motor Function, Muscle Performance, and Range of Motion Associated with Connective Tissue Dysfunction

  • 4E: Impaired Joint Mobility, Motor Function, Muscle Performance, and Range of Motion Associated with Localized Inflammation

  • 6B: Impaired Aerobic Capacity/Endurance Associated with Deconditioning


Graves disease. Note the proptosis of the eyes, thyroid acropachy, and the thyroid dermopathy on the pretibial region. (From Goldsmith LA, Katze S, Gilchrest B, Paller A, Leffel D, Wolff K. Fitzpatrick’s Dermatology in General Medicine, 8th ed. Copyright © The McGraw-Hill Companies, Inc. All rights reserved.)

Graphic Jump Location


A 35-year-old female presents with complaints of a rapid heartbeat, excessive sweating, difficulty sleeping, irritability, and weight loss of 25 lb in the last 4 months despite having an increased appetite. Upon further questioning, she reports frequently feeling hot, having increased loose stools or diarrhea, and thinning of her hair. She has no other past medical history. Family history reveals a history of maternal “thyroid issues” and paternal hypertension. Past routine physical examinations document heart rates in the 70s and blood pressures around 110/70, but today her blood pressure is 135/90 and heart rate is 110 beats per minute. On examination, you note a fine tremor in her hands, bulging eyes, pretibial myxedema (PTM), and a diffusely enlarged thyroid.




  • Graves disease is an autoimmune disorder

  • Overactivity of the thyroid gland (hyperthyroidism)

  • Produces excessive amount of thyroid hormone

  • Enlargement of the thyroid gland

Essentials of Diagnosis

  • Diagnosis is made by the symptoms

  • Thyroid hormone test

  • Onset of symptoms is often insidious

  • Symptoms build over a period of time, which can delay diagnosis

General Considerations

  • Diagnosis for more occult problems may take time and require intensive medical diagnostic testing

  • May cause pathology in multiple organ systems

    • GI: Liver

    • Cardiovascular: Heart, peripheral circulation, blood pressure

    • Integumentary

  • May result in secondary problems

    • Aerobic capacity and muscle endurance impairment

    • Sarcopenia

    • Weakness/impaired muscle performance

    • Musculoskeletal problems

    • Neuromuscular problems

    • Weight gain indicating the need for PT intervention, depending on severity

Want remote access to your institution's subscription?

Sign in to your MyAccess profile while you are actively authenticated on this site via your institution (you will be able to verify this by looking at the top right corner of the screen - if you see your institution's name, you are authenticated). Once logged in to your MyAccess profile, you will be able to access your institution's subscription for 90 days from any location. You must be logged in while authenticated at least once every 90 days to maintain this remote access.


About MyAccess

If your institution subscribes to this resource, and you don't have a MyAccess profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus.

Subscription Options

AccessPhysiotherapy Full Site: One-Year Subscription

Connect to the full suite of AccessPhysiotherapy content and resources including interactive NPTE review, more than 500 videos, Anatomy & Physiology Revealed, 20+ leading textbooks, and more.

$595 USD
Buy Now

Pay Per View: Timed Access to all of AccessPhysiotherapy

24 Hour Subscription $34.95

Buy Now

48 Hour Subscription $54.95

Buy Now

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.