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++

ADAAdenosine deaminase

++

ADCC Antibody-dependent cell-mediated cytotoxicity

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AIDSAcquired immunodeficiency syndrome

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APC Antigen-presenting cell

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BCR B-cell receptor

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BTK Bruton’s tyrosine kinase

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C1, C2, etc Complement factor 1, complement factor 2, etc

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cAMP Cyclic adenosine monophosphate

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CCR5 CC-subfamily chemokine receptor 5

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CD Clusters of differentiation

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CD4 Helper T-cell subset

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CD8 Cytotoxic T-cell subset

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CTL Cytotoxic lymphocyte

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CXCR5 CXC-subfamily chemoreceptor 5

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F(ab) Antigen-binding fragment

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Fc Crystallizable fragment

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FcεRI High-affinity IgE receptor

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FcγR Fc gamma receptor

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GM-CSFGranulocyte-macrophage colony-stimulating factor

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HBV Hepatitis B virus

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HCV Hepatitis C virus

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HIVHuman immunodeficiency virus

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HPV Human papillomavirus

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HSV Herpes simplex virus

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HZV Herpes zoster virus

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ICAM-1 Intercellular adhesion molecule-1

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IFN-γ Interferon-γ

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Ig Immunoglobulin

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IVIG Intravenous immunoglobulin

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IL-1, IL-2, etc Interleukin-1, interleukin-2, etc.

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JAK Janus kinase

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JC Jakob–Creutzfeldt

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LAK cell Lymphokine-activated killer cell

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LPS Lipopolysaccharide

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MAC Mycobacterium avium complex

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MHCMajor histocompatibility complex

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NADPHNicotinamide adenine dinucleotide phosphate

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NK Natural killer cells

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PAF Platelet-activating factor

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PGDProstaglandin D

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PNP Purine nucleoside phosphorylase

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PTK Protein tyrosine kinase

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RAG Recombination-activating gene

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RANTES Chemokine regulated on activation normal T expressed and secreted

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RAST Radioallergosorbent test

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SCID Severe combined immunodeficiency disease

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TAME  N-α-p-tosyl-l-arginine methylester-esterase

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TCR T-cell receptor

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TH1 Helper T 1 subset

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TH2 Helper T 2 subset

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TH17 Helper T subset secreting IL-17

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TREG Helper T subset with regulatory function

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Tr1 Regulatory T-cell subset

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TLR Toll-like receptor

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TNF Tumor necrosis factor

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TSH Thyroid-stimulating hormone

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V-CAM-1 Vascular cell adhesion molecule-1

++

VIP Vasoactive intestinal peptide

++

XLA X-linked agammaglobulinemia

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XSCID X-linked severe combined immunodeficiency disease

++

ZAP-70 Protein tyrosine kinase ZAP-70

++

The function of the immune system is to protect the host from invasion of foreign organisms by distinguishing “self” from “nonself.” Such a system is necessary for survival. A well-functioning immune system not only protects the host from ...

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