Skip to Main Content


  • Enlarged thyroid


  • 240.9 Goiter, unspecified
  • 241.0 Nontoxic uninodular goiter
  • 241.1 Nontoxic multinodular goiter
  • 241.9 Unspecified nontoxic nodular goiter
  • 242 Thyrotoxicosis with or without goiter
  • 242.0 Toxic diffuse goiter
  • 242.00 Toxic diffuse goiter without mention of thyrotoxic crisis or storm
  • 242.01 Toxic diffuse goiter with mention of thyrotoxic crisis or storm
  • 242.1 Toxic uninodular goiter
  • 242.10 Toxic uninodular goiter without mention of thyrotoxic crisis or storm
  • 242.11 Toxic uninodular goiter with mention of thyrotoxic crisis or storm
  • 242.2 Toxic multinodular goiter
  • 242.20 Toxic multinodular goiter without mention of thyrotoxic crisis or storm
  • 242.21 Toxic multinodular goiter with mention of thyrotoxic crisis or storm
  • 242.3 Toxic nodular goiter unspecified type
  • 242.30 Toxic nodular goiter, unspecified type, without mention of thyrotoxic crisis or storm
  • 242.31 Toxic nodular goiter, unspecified type, with mention of thyrotoxic crisis or storm
  • 242.40 Thyrotoxicosis from ectopic thyroid nodule without mention of thyrotoxic crisis or storm


  • E01.1 Iodine-deficiency related multinodular (endemic) goiter
  • E01.2 Iodine-deficiency related (endemic) goiter, unspecified
  • E03.0 Congenital hypothyroidism with diffuse goiter
  • E03.1 Congenital hypothyroidism without goiter
  • E04 Other nontoxic goiter
  • E04.0 Nontoxic diffuse goiter
  • E04.2 Nontoxic multinodular goiter
  • E04.8 Other specified nontoxic goiter
  • E04.9 Nontoxic goiter, unspecified
  • E05.00 Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm
  • E05.0 Thyrotoxicosis with diffuse goiter
  • E05.2 Thyrotoxicosis with toxic multinodular goiter
  • E07.1 Dyshormogenetic goiter
  • P72.0 Neonatal goiter, not elsewhere classified




  • Enlarged thyroid gland, can result in decreased production of thyroid hormone
  • Prolonged elevation of thyroid stimulating hormone (TSH)
  • Weight gain or loss
  • May range from single or small nodules to significant enlargement
  • Multinodular goiter4
  • Enlargement can limit neck mobility and swallowing


Essentials of Diagnosis


  • Fatigue
  • Decreased activity tolerance
  • Sensitivity to cold
  • Abnormal thyroid function tests
  • Thyroid enlargment


General Considerations


  • Diagnosis for more occult problems may take time and require intensive diagnostic testing, inability to afford testing and medications, noncompliance with medication regimen
  • May cause pathology in multiple organ systems
    • GI: liver
    • Cardiovascular: heart, peripheral circulation, blood pressure
    • Integumentary
  • May result in secondary problems indicating need for PT intervention: aerobic capacity and muscle endurance impairment, sarcopenia, weakness, musculoskeletal problems, neuromuscular problems, weight gain
  • Hyperlipidemia
  • Can result in hyperthyroid




  • Can occur in anyone throughout lifespan, beginning at birth (1 in 4,000 infants affected)
  • Estimated 5 million people affected in the U.S., and an equal number undiagnosed
  • Higher incidence in women and people aged 60 years and older


Signs and Symptoms


  • Nausea
  • Vomiting
  • Diarrhea
  • Coughing
  • Sweating
  • Shaking agitation
  • Hoarseness
  • Dizziness with arms overhead
  • Difficulty swallowing
  • Sensitivity to cold
  • Slowed or rapid heart rate
  • Constipation
  • Joint or muscle pain
  • Paleness
  • ...

Want remote access to your institution's subscription?

Sign in to your MyAccess profile while you are actively authenticated on this site via your institution (you will be able to verify this by looking at the top right corner of the screen - if you see your institution's name, you are authenticated). Once logged in to your MyAccess profile, you will be able to access your institution's subscription for 90 days from any location. You must be logged in while authenticated at least once every 90 days to maintain this remote access.


Create a Free MyAccess Profile

* Required Fields

Note: If you have registered for a MyAccess profile on any of the Access sites, you can use the same MyAccess login credentials across all sites.

Passwords must be between 6 and 40 characters long (no whitespace), cannot contain characters #, &, and must contain:
  • at least one lowercase letter
  • at least one uppercase letter
  • at least one digit

Benefits of a MyAccess Profile:

  • Remote access to the site off-campus on any device
  • Notification of new content via custom alerts
  • Bookmark your favorite content such as chapters, figures, tables, videos, cases and more
  • Save and download images to PowerPoint
  • Self-Assessment quizzes saved for quick review
  • Custom Curriculum access for both instructors and learners

Subscription Options

AccessPhysiotherapy Full Site: One-Year Subscription

Connect to the full suite of AccessPhysiotherapy content and resources including interactive NPTE review, more than 500 videos, Anatomy & Physiology Revealed, 20+ leading textbooks, and more.

$595 USD
Buy Now

Pay Per View: Timed Access to all of AccessPhysiotherapy

24 Hour Subscription $34.95

Buy Now

48 Hour Subscription $54.95

Buy Now

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.