TY - CHAP M1 - Book, Section TI - Chapter 9. Abnormalities of Blood Supply A1 - Chandrasoma, Parakrama A1 - Taylor, Clive R. Y1 - 1998 N1 - T2 - Concise Pathology, 3e AB - The maintenance of adequate blood circulation is a highly complex process that depends on proper function of the heart, the integrity of the vasculature, and the maintenance of a delicate balance between the coagulation and fibrinolytic systems. Failure of blood supply to a tissue (ischemia) may be localized, due to arterial obstruction or deficient venous drainage, leading to infarction (ischemic necrosis of tissue); or generalized, due to severe decrease in cardiac output, leading to a generalized decrease in tissue perfusion (shock). SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=184085 ER -