RT Book, Section
A1 Frankel, Timothy L.
A1 Sonnenday, Christopher J.
A2 Hammer, Gary D.
A2 McPhee, Stephen J.
SR Print(0)
ID 1156658935
T1 Disorders of the Exocrine Pancreas
T2 Pathophysiology of Disease: An Introduction to Clinical Medicine, 8e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260026504
LK accessphysiotherapy.mhmedical.com/content.aspx?aid=1156658935
RD 2024/04/19
AB The  pancreas  is  a  gland  with  both  exocrine  and  endocrine  functions.  The  exocrine  pancreas  contains  acini,  which  secrete  pancreatic  juice  into  the  duodenum  through  the  pancreatic  ducts  (Figure  15–1).  Pancreatic  juice  contains  a  number  of  enzymes,  some  of  which  are  initially  secreted  as  zymogens  in  an  inactive  form.  Once  activated,  these  enzymes  help  digest  food  and  prepare  it  for  absorption  in  the  intestine.  Disorders  interfering  with  normal  pancreatic  enzyme  activity  (pancreatic  insufficiency)  cause  fat  maldigestion  and  steatorrhea  (fatty  stools).  Pathology  of  the  exocrine  pancreas  results  from  inflammation  (acute  pancreatitis,  chronic  pancreatitis),  neoplasm  (ductal  adenocarcinoma,  neuroendocrine  tumors,  other  pancreatic  neoplasms),  or  duct  obstruction  by  stones  or  abnormally  viscid  mucus  (cystic  fibrosis).