RT Book, Section A1 Chandrasoma, Parakrama A1 Taylor, Clive R. SR Print(0) ID 190198 T1 Chapter 46. The Endocrine Pancreas (Islets of Langerhans) T2 Concise Pathology, 3e YR 1998 FD 1998 PB The McGraw-Hill Companies PP New York, NY SN 9780838514993 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=190198 RD 2024/04/24 AB The islets of Langerhans are microscopic structures 50–250 μm in diameter. They are scattered throughout the pancreas, with a maximum density in the tail. The islets appear to have a great reserve capacity; islet dysfunction is not a major problem even after 90% of the pancreas is removed in a distal pancreatectomy. The islets are not connected to the exocrine duct system; the hormonal products are secreted directly into the bloodstream.