RT Book, Section
A1 Kemp, Walter L.
A1 Burns, Dennis K.
A1 Brown, Travis G.
SR Print(0)
ID 57050916
T1 Chapter 4. Neoplasia
T2 Pathology: The Big Picture
YR 2008
FD 2008
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-147748-2
LK accessphysiotherapy.mhmedical.com/content.aspx?aid=57050916
RD 2024/04/19
AB Neoplasia  is  new  growth.  The  terms  benign  and  malignant  correlate  to  the  course  of  the  neoplasm.  Benign  neoplasms  stay  localized  in  one  place;  malignant  neoplasms  invade  surrounding  tissue  and,  in  most  cases,  can  metastasize  to  distant  organs.  To  become  neoplastic,  a  normal  cell  must  develop  mutations  that  allow  it  to  no  longer  obey  boundaries  of  adjacent  cells,  thus  allowing  for  uncontrolled  growth,  and  the  neoplasm  must  be  able  to  produce  its  own  blood  supply.  If  the  neoplasm  is  malignant,  the  cells  must  also  gain  the  ability  to  invade  the  basement  membrane  and  surrounding  tissue,  enter  the  blood  stream,  and  spread  to  and  grow  within  distant  organs.