RT Book, Section A1 Kemp, Walter L. A1 Burns, Dennis K. A1 Brown, Travis G. SR Print(0) ID 57054609 T1 Chapter 16. Pathology of the Kidney and Bladder T2 Pathology: The Big Picture YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-147748-2 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=57054609 RD 2024/04/18 AB In this chapter, the pathology of the kidney is organized into four anatomic categories: diseases of the glomeruli, tubules, interstitium, and vessels. Diseases that affect the glomeruli often have an immunologic etiology, whereas those that affect the tubules and interstitium usually have an infectious or toxic etiology. Early in the disease process, most disorders predominantly affect one of the anatomic structures listed above. Over time, however, the entire kidney usually becomes diseased. Because of the large physiologic reserve of the kidneys, many diseases do not become clinically apparent until the majority of the organ is affected, making subtle abnormalities in laboratory findings the only early indication of renal disease. Recognition of these patterns of abnormalities, pathologic findings, and clinical presentation is perhaps more important to renal pathology than in any other organ system. This chapter describes acute and chronic renal failure, disorders of volume regulation, glomerular diseases, tubulointerstitial diseases, nephrolithiasis, cystic diseases of the kidney, renal tumors, pathology of the bladder, acid-base disorders, and electrolyte disorders.