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CHAPTER TWO. Healing Response in Acute and Chronic Wounds

A contaminated, full thickness wound of significant size would most likely undergo which category(s) of healing?

a. Category 1 (primary healing)

b. Category 2 (delayed primary healing)

c. Category 3 (secondary healing)

d. Category 4 (chronic wound healing)

Critical wound healing is the time required for a wound to heal to the point where it becomes self-supportive and function has been restored. T or F?

a. True

b. False

Which wound healing phase is characterized by granulation tissue?

a. Hemostasis

b. Inflammation

c. Proliferation/maturation

d. Remodeling

When does inflammation begin?

a. Immediately post-injury

b. When neo-angiogenesis is evident in the wound bed

c. When bleeding is fully arrested

d. When wound contraction is evident

When does proliferation begin?

a. Proliferation overlaps with inflammation with epithelial cell migration at the wound edges.

b. When the damaged tissue has largely been replaced and begins to regain strength with the deposition of collagen, primarily type III.

c. When there is an expansion of blood vessels (angiogenesis) and the initiation of wound contraction to complement closure that is driven by the presence of myofibroblasts.

d. When capillary buds are first visible in the wound bed.

During remodeling, Type III collagen is replaced with

a. Type I collagen

b. Type II collagen

c. Type IV collagen

d. Type V collagen

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