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CONDITION/DISORDER SYNONYMS
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Creutzfeldt–Jakob disease (CJD)
Fatal familial insomnia
Gerstmann– Sträussler –Scheinker syndrome
Kuru
Transmissible spongiform encephalopathies (TSEs)
Variant Creutzfeldt–Jakob disease (vCJD)
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046.0 Kuru
046.1 Jakob–Creutzfeldt disease
046.11 Variant Creutzfeldt–Jakob disease
046.19 Other and unspecified Creutzfeldt–Jakob disease
046.2 Subacute sclerosing panencephalitis
046.3 Progressive multifocal leukoencephalopathy
046.7 Other specified prion diseases of central nervous system
046.71 Gerstmann–Sträussler–Scheinker syndrome
046.72 Fatal familial insomnia
046.79 Other and unspecified prion disease of central nervous system
046.8 Other specified slow virus infection of central nervous system
046.9 Unspecified slow virus infection of central nervous system
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A81.00 Creutzfeldt–Jakob disease, unspecified
A81.01 Variant Creutzfeldt–Jakob disease
A81.09 Other Creutzfeldt–Jakob disease
A81.1 Subacute sclerosing panencephalitis
A81.2 Progressive multifocal leukoencephalopathy
A81.81 Kuru
A81.82 Gerstmann–Sträussler–Scheinker syndrome
A81.83 Fatal familial insomnia
A81.89 Other atypical virus infections of central nervous system
A81.9 Atypical virus infection of central nervous system, unspecified
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PREFERRED PRACTICE PATTERNS1
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5A: Primary Prevention/Risk Reduction for Loss of Balance and Falling
5C: Impaired Motor Function and Sensory Integrity Associated with Nonprogressive Disorders of the Central Nervous System—congenital origin or acquired in infancy or childhood
5D: Impaired Motor Function and Sensory Integrity Associated with Nonprogressive Disorders of the Central Nervous System—acquired in adolescence or adulthood
5I: Impaired Arousal, Range of Motion and Motor Control Associated with Coma, Near Coma, or Vegetative State
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PATIENT PRESENTATION
A 52-year-old man was admitted to the hospital following a fall that resulted in a fractured right ankle. The ankle fractured was surgically repaired. The family reports that the patient had become increasingly unstable while walking; he struggles to get out of his favorite chair at home, and needs help with getting dressed. He is also very confused and seems to struggle with remembering things from one moment to the next. These concerns started approximately 3 weeks ago. Before that time, he was completely independent and worked successfully at a job that required him to think and act quickly.
Physical therapy was ordered in the hospital to address ambulation, non-weight bearing on the right lower extremity.
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Progressive neurodegenerative disorders
Abnormal pathogenic agent
Leads to brain damage
Affects the central nervous system
Rapidly progressive and fatal
Human prion diseases
Animal prion diseases
Bovine spongiform encephalopathy (BSE)
Chronic wasting disease (CWD)
Scrapie
Transmissible mink encephalopathy
Feline spongiform encephalopathy
Ungulate spongiform encephalopathy
Three classifications
Sporadic
Familial
Acquired
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