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Condition/Disorder Synonym

  • Diffuse thyrotoxic goiter

ICD-9-CM Codes

  • 242.0 Toxic diffuse goiter

  • PT diagnoses codes that may be secondary to thyroid disorders.

    • 315.4 Developmental coordination disorder

    • 709.2 Scar conditions and fibrosis of the skin

    • 719.70 Difficulty in walking involving joint site unspecified

    • 728.2 Muscular wasting and disuse atrophy, not elsewhere classified

    • 728.89 Other disorders of muscle, ligament, and fascia

    • 729.9 Other and unspecified disorders of soft tissue

    • 781.2 Abnormality of gait

    • 782.3 Edema

    • 786.0 Dyspnea and respiratory abnormalities

    • 786.05 Shortness of breath

ICD-10-CM Codes

  • E05 Thyrotoxicosis (hyperthyroidism)

  • E05.0 Thyrotoxicosis with diffuse goiter

Preferred Practice Patterns1

Key Features


Essentials of Diagnosis

  • Diagnosis is made by the symptoms

  • Thyroid hormone test

  • Onset of symptoms is often insidious

  • Symptoms build over a period of time, which can delay diagnosis

General Considerations

  • Diagnosis for more occult problems may take time and require intensive medical diagnostic testing

  • May cause pathology in multiple organ systems

    • GI: liver

    • Cardiovascular: heart, peripheral circulation, blood pressure

    • Integumentary

  • May result in secondary problems

    • Aerobic capacity and muscle endurance impairment

    • Sarcopenia

    • Weakness/impaired muscle performance

    • Musculoskeletal problems

    • Neuromuscular problems

    • Weight gain indicating the need for PT intervention, depending on severity


  • Higher incidence in young women: 5 to 10 times more common

  • Most common form of hyperthyroidism in children

  • Presents during early adolescence

  • Less common in blacks

  • Gender: females at greater risk

Clinical Findings

Signs and Symptoms

  • PTs may treat conditions caused by hyperthyroid or treat patients with hyperthyroid for other pathologies that are unrelated

    • Graves' ophthalmopathy: red or swollen eyes, bulging or protruding eyeballs, impaired vision, inflammation, light sensitivity

    • Eye irritation

    • Double vision

    • Enlarged thyroid

    • Fatigue

    • Weight loss

    • Bulging of eyes

    • Pretibial myxedema (PTM)

    • Possible goiter

    • Tachycardia

    • Cardiac: atrial fibrillation, arrhythmias, palpitations

    • Racing/rapid pulse

    • High blood pressure

    • Hyperactivitiy

    • Difficulty concentrating and focusing

    • Heat intolerance

    • Sweating, clammy skin

    • Confusion, disorientation

    • Diuresis

    • Muscle Weakness

    • Tremors

    • Neck pain

    • Unexplained weight loss with inability to gain weight

    • Difficulty swallowing

    • Change in voice

    • Heart disease

    • Dyspnea, shortness of breath with exertion

    • Airway obstruction

    • Increased appetite

    • Menstrual disturbance, irregularity

    • Increased bowel frequency

    • Breast development in men

    • Clammy skin

    • Diarrhea

    • Hair loss

    • Hand tremor

    • Itching

    • Nausea and vomiting

    • Skin blushing or flushing

    • Difficulty sleeping

    • Osteoporosis

    • Nervousness/anxiety

Functional Implications


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