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Condition/Disorder Synonyms

  • Primary Sjögren's (dry eyes and mouths only)

  • Secondary Sjögren's (associated with other immune disorders)

ICD-9-CM Codes

  • 710.2 Sicca syndrome

  • PT diagnoses/treatment diagnoses that may be associated with immune disorders affecting movement

    • 315.4 Developmental coordination disorder

    • 718.07 Articular cartilage disorder, ankle and foot

    • 718.03 Articular cartilage disorder, forearm

    • 718.04 Articular cartilage disorder, hand

    • 718.45 Contracture of joint, pelvic region and thigh

    • 719.39 Palindromic rheumatism involving multiple sites

    • 719.4 Pain in joint

    • 728.2 Muscular wasting and disuse atrophy, not elsewhere classified

    • 729.9 Other and unspecified disorders of soft tissue

    • 729.1 Myalgia and myositis, unspecified

    • 729.9 Other disorders of soft tissue

    • 736.9 Acquired deformity of limb site unspecified

    • 780.7 Malaise and fatigue

    • 781.2 Abnormality of gait

    • 782.3 Edema

    • 786.0 Dyspnea and respiratory abnormalities

    • 786.05 Shortness of breath

    • 728.89 Other disorders of muscle, ligament, and fascia

ICD-10-CM Codes

  • M35.00 Sicca syndrome, unspecified

  • M35.01 Sicca syndrome with keratoconjunctivitis

Preferred Practice Patterns1

Key Features


  • Condition in which healthy tissue is mistaken by the body as foreign substances

  • Affects the exocrine glands

  • Limits production of body secretions

  • Multiple body system involvement

  • Onset often vague with misdiagnosis

Essentials of Diagnosis

  • Must be made by a physician and confirmed by medical diagnostic testing

  • History

  • Presence of markers

  • Dry eyes and mouth

  • Elimination of other diseases

General Considerations

  • Specific diagnosis may take time and require intensive medical diagnostic testing

  • May result in secondary problems such as

    • Aerobic capacity and muscle endurance impairment

    • Sarcopenia

    • Weakness/impaired muscle performance

    • Musculoskeletal problems

    • Neuromuscular problems

    • Weight loss, indicating the need for PT intervention depending on severity

  • Because Sjögren's and other immune disorders frequently refer pain or are causative of pain in various body areas, individuals may get referred to PT inappropriately or appropriately; inappropriate referral may be such as when referred to the lower back or upper back or chest

  • History of heartburn or indigestion may be indicative of GI or cardiac problems or directly related to Sjögren's


  • Females more likely than males

  • Adults > 40 years of age

  • Can affect individuals of all ages, but is rare in children

  • Some indication of genetic familial tendency

  • More likely if there is a systemic rheumatic disease such as systemic lupus erythematosus (SLE) or rheumatoid arthritis

  • Estimated 1 to 4 million in U.S.

Clinical Findings

Signs and Symptoms

  • The signs and symptoms indicated below may be characteristic of multiple immune ...

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