American College of Sports Medicine. ACSM’s Guidelines for Exercise Testing and Prescription. Philadelphia, PA: Lippincott Williams & Wilkins, 2014.
American Heart Association. Statement on exercise. Benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the Committee on Exercise and Cardiac Rehabilitation of the Council on Clinical Cardiology, American Heart Association. Circulation 86: 340–344, 1992.
Bateman LA, Slentz CA, Willis LH, Shields AT, Piner LW, Bales CW,
et al Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted Risk Reduction Intervention Through Defined Exercise–STRRIDEAT/RT). American Journal of Cardiology 108: 838–844, 2011.
Beaglehole R, Bonita R, and Kjellström T. Basic Epidemiology. Geneva: World Health Organization, 1993.
Beavers KM, Ambrosius WT, Nicklas, BJ, and Rejeski WJ. Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults. Journal of the American Geriatrics Society 61: 1089–1094, 2013.
Beavers KM, Brinkly TE, and Nicklas BJ. Effect of exercise training on chronic inflammation. Clinica Chemica Acta 411: 785–793, 2010.
Beavers KM, Hsu F-C, Isom S, Kritchevsky SB, Church T, Goodpaster B,
et al Long-term physical activity and inflammatory biomarkers in older adults. Medicine & Science in Sports & Exercise 42: 2189–2196, 2010.
Blair SN, Smith GD, Lee IM, Fox K, Hillsdon M, McKeown RE,
et al A tribute to Professor Jeremiah Morris: the man who invented the field of physical activity epidemiology. Annals of Epidemiology 20: 651–660, 2010.
Booth, FW, Roberts CK, and Laye MJ. Lack of exercise is a major cause of chronic diseases. Journal of Comparative Physiology 2: 1143–1211, 2012.
Bouchard C, Shephard R, Stevens T, Sutton J, and McPherson B. Exercise, fitness, and health: the consensus statement. In Exercise, Fitness, and Health, edited by Bouchard C, Shephard RJ, Stevens T, Sutton JR, and McPherson BD. Champaign, IL: Human Kinetics, 1990, pp. 3–28.
Brandt C and Pedersen BK. The role of exercise-induced myokines in muscle homeostasis and the defense against chronic disease. Journal of Biomedicine and Biotechnology Article ID: 520258, 2010.
Buckley DI, Fu R, Freeman M, Rogers K, and Helfand M. C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analysis for the U. S. Preventive Services Task Force. Annals of Internal Medicine 151: 483–495, 2009.
Caspersen C and Heath G. The risk factor concept of coronary heart disease. In Resource Manual for Guidelines for Graded Exercise Testing and Prescription, edited by Blair SN, Painter P, Pate R, Smith L, and Taylor C. Philadelphia, PA: Lea & Febiger, 1988, pp. 111–125.
Caspersen CJ. Physical activity epidemiology: concepts, methods, and applications to exercise science. Exercise and Sport Science Reviews 17: 423–473, 1989.
Church TS. Exercise in obesity, metabolic syndrome, and diabetes Progress in Cardiovascular Diseases 53: 412–418, 2011.
Church TS, Earnest CP, Thompson AM, Priest EL, Rodarte RQ, Saunders T,
et al Exercise without weight loss does not reduce c-reactive protein: the INFLAME study. Medicine & Science in Sports & Exercise 42: 708–716, 2010.
Danaei G, Ding EL, Mozaffarian D, Taylor B, Rehm J, Murray CJL,
et al The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic factors. PLOS Medicine 6: e1000058, doi:10.1371, 2009.
Dawber T. The Framingham Study. Cambridge: Harvard University Press, 1980.
Després J-P. Abdominal obesity and cardiovascular disease: is inflammation the missing link? Canadian Journal of Cardiology 28: 642–652, 2012.
Ebrahim S, Taylor F, Ward K, Beswick A, Burke M, and Smith GD. Multiple risk factor interventions for primary prevention of coronary heart disease. Cochrane Database Systym Reviews 1: CD001561, 2011.
Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G,
et al Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome. JAMA[JAMA and JAMA Network Journals Full Text]
292: 1440–1446, 2004.
Gleeson M, Bishop NC, Stensel DJ, Lindley MR, Mastana SS, and Nimmo MA. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nature Reviews Immunology 11: 607–615, 2011.
Golbidi S, Mesdaghinia A, and Laher I. Exercise and the metabolic syndrome. Oxidative Medicine and Cellular Longevity Volume 2012, No. 349710.
Grattagliano I, Palmieri VO, Portincasa P, Moschetta A, and Palasciano G. Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis. The Journal of Nutritional Biochemistry 19: 491–504, 2008.
Gustafson B. Adipose tissue, inflammation and atherosclerosis. Journal of Atherosclerosis and Thrombosis 17: 332–341, 2010.
Hardman WE. Diet components can suppress inflammation and reduce cancer risk. Nutrition Research and Practice 8(3): 233–240, June 2014; doi:10.4162/nrp.2014.8.3.233. Epub 2014 May 15
Imayama I, Ulrich CM, Alfano CM, Wang CC, Xiao LR, Wener MH,
et al Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial. Cancer Research 72: 2314–2326, 2012.
Kaplan NM. The deadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Archives of Internal Medicine 149: 1514–1520, 1989.
Kasaniemi YA, Danforth JE, Jensen MD, Kopelman PG, Lefebvre P, and Reeder BA. Dose-response issues concerning physical activity and health: an evidence-based symposium. Medicine & Science in Sports & Exercise 33 (Suppl): S351–358, 2001.
Lakka TA and Laaksonen DE. Physical activity in prevention and treatment of the metabolic syndrome. Applied Physiology, Nutrition, and Metabolism 32: 76–88, 2007.
Lavie CJ, Church TS, Milani RV, and Earnest CP. Impact of physical activity, cardiorespiratory fitness, and exercise training on markers of inflammation. Journal of Cardiopulmonary Rehabilitation and Prevention 31: 137–145, 2011.
Libby P. Atherosclerosis: the new view. Scientific American May 2002: 46–55, 2002.
Libby P, Okamoto Y, Rocha VZ, and Folco E. Inflammation in atherosclerosis. Circ J 74: 213–220, 2010.
Libby P, Ridker PM, and Maseri A. Inflammation and atherosclerosis. Circulation Journal 105: 1135–1143, 2002.
MacMahon B and Pugh T. Epidemiology. Boston, MA: Little, Brown, 1970.
Mathur N and Pedersen BK. Exercise as a means to control low-grade systemic inflammation. Mediators of Inflammation 2008: 1–6, 2008.
Monteiro R and Azavedo I. Chronic inflammation in obesity and the metabolic syndrome. Mediators of Inflammation Article ID 289645, 2010.
Morris JN, Chave SP, Adam C, Sirey C, Epstein L, and Sheehan DJ. Vigorous exercise in leisure-time and the incidence of coronary heart-disease. Lancet 1: 333–339, 1973.
Morris JN, Heady JA, Raffle PA, Roberts CG, and Parks JW. Coronary heart disease and physical activity of work. Lancet 265: 1111–1120; concl, 1953.
National Heart Blood and Lung Institute. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel. Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) executive summary. NIH Publication No. 02–5285, 2002.
Nimmo MA, Leggate M, Viana JL, and King JA. The effect of physical activity on mediators of inflammation. Diabetes, Obesity and Metabolism 15 (Suppl. 3): 51–60, 2013.
Ogden CL, Carroll MD, Kit BK, and Flegal KM. Prevalence of obesity in the United States 2009–2010. National Center for Health Statistics Data Brief. No. 82, 2012.
Paffenbarger RS, Jr., Blair SN, and Lee I-M. A history of physical activity, cardiovascular health and longevity: the scientific contributions of Jeremy N. Morris, DSc, DPH, FRCP. International Journal of Epidemiology 30: 1184–1192, 2001.
Paffenbarger RS, Jr., Hyde RT, Wing AL, Lee IM, Jung DL, and Kampert JB. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. The New England Journal of Medicine 328: 538–545, 1993.
Paffenbarger RS, Jr., Laughlin ME, Gima AS, and Black RA. Work activity of longshoremen as related to death from coronary heart disease and stroke. The New England Journal of Medicine 282: 1109–1114, 1970.
Paffenbarger RS, Jr., Wing AL, and Hyde RT. Physical activity as an index of heart attack risk in college alumni. American Journal of Epidemiology 108: 161–175, 1978.
Palmefors H, DuttaRoy S, Rundqvist B, and Borjesson M. The effect of physical activity or exercise on key biomarkers in atherosclerosis—A systematic review. Atherosclerosis 235: 150–161, 2014.
Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C,
et al Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA[JAMA and JAMA Network Journals Full Text]
273: 402–407, 1995.
Pedersen BK. Edward F. Adolph distinguished lecture: muscle as an endocrine organ: IL-6 and other myokines. Journal of Applied Physiology 107: 1006–1014, 2009.
Powell KE, Thompson PD, Caspersen CJ, and Kendrick JS. Physical activity and the incidence of coronary heart disease. Annual Review of Public Health 8: 253–287, 1987.
Powell KE, Paluch AE, and Blair SN. Physical activity for health: what kind? How much? How intense? On top of what? Annual Review of Public Health 32: 349–365, 2011.
Rana JS, Nieuwdorp M, Jukema JW, and Kastelein JJP. Cardiovascular metabolic syndrome—an interplay of obesity, inflammation, diabetes and coronary heart disease. Diabetes, Obesity and Metabolism 9: 218–232, 2007.
Reaven GM. Banting lecture 1988. Role of insulin
resistance in human disease. Diabetes
37: 1595–1607, 1988.
Richard C, Couture P, Desroches S, and Lamarche B. Effect of the Mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome. Obesity 21: 541–557, 2013.
Ringseis R, Eder K, Mooren FC, Krüger K. Metabolic signals and innate immune activation in obesity and exercise. Exercise Immunology Review 21: 58–68, 2015.
Rizvi AA. Hypertension, obesity, and inflammation: the complex designs of the deadly trio. Metabolic Syndrome and Related Disorders 8: 287–294, 2010.
Roberts CK and Sindhu KK. Oxidative stress and the metabolic syndrome. Life Sciences 84: 705–712, 2009.
Rockett I. Population and health: an introduction to epidemiology. Population Bulletin Journal 49: 1–48, 1994.
Stallones R. Public Health Monograph 76. Washington, DC: U.S. Government Printing Office, 1966.
U. S. Department of Health and Human Services. Physical Activity and Health: A Report of the Surgeon General. Washington, DC: U.S. Government Printing Office, 1996.
U.S. Department of Health Education and Welfare. Healthy People: The Surgeon General’s Report on Health Promotion and Disease Prevention. Washington, DC: U.S. Government Printing Office, 1979.
Wang Z and Nakayama T. Inflammation, a link between obesity and cardiovascular disease. Mediators of Inflammation Article ID 535918, 2010.
Wassink AM, Olijhoek JK, and Visseren FL. The metabolic syndrome: metabolic changes with vascular consequences. European Journal of Clinical Investigation
37: 8–17, 2007.
Xu J, Murphy SL, Kochanek KD, and Bastian BA. Deaths: final data for 2013. National Vital Statistics Reports
64: 1–118, 2016.
Yoon SS, Burt V, Louis T, and Carroll, MD. Hypertension among adults in the United States, 2009–2010. National Center for Health Statistics Data Brief. No. 107, 2012.
You T, Arsenis NC, Disanzo BL, and LaMonte MJ. Effects of exercise training on chronic inflammation in obesity. Sports Medicine
43: 243–256, 2013.