Skip to Main Content

Chapter 3: Pharmacokinetics and Pharmacogenomics

Which of the following requires the conversion of adenosine triphosphate (ATP) to adenosine diphosphate (ADP) as a protein moves a molecule against its concentration gradient?

a. Active transport

b. Facilitated transport

c. Passive diffusion

d. Endocytosis

At what pH must the urine be to optimally trap an acid with a pKa of 7.50?

a. 7.75

b. 8.50

c. 7.25

d. 5.50

Which of the following is not a parenteral route of administration?

a. Intravenous

b. Transdermal

c. Rectal

d. Inhalation

The drug has a volume of distribution of 0.20 L/kg. What is the distribution of the drug in the body?

a. Limited to the plasma

b. Concentrated outside of the plasma

c. Total body distribution

d. Limited to plasma and extracellular space

The plasma concentration of a drug is 100 mcg/L and its half-life is 3 hours. What is the concentration of the drug 12 hours later?

a. 6.25 mcg/L

b. 25.0 mcg/L

c. 3.125 mcg/L

d. 12.50 mcg/L

The half-life (t1/2) is calculated by which of the following formulas?

a. Clearance multiplied by the drug dose

b. Volume of distribution divided by the clearance

c. Volume of distribution multiplied by the clearance

d. Volume of distribution multiplied by the drug dose

Which of the following is not involved in a maintenance dosage for a drug?

a. Clearance

b. Half-life

c. Volume of distribution

d. Bioavailability

Which of ...

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.