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Chapter 5: Drugs Affecting the Cholinergic System

Inhibition of muscarinic receptors may result in which of the following adverse effects?

a. Muscle weakness

b. Hyperactive bladder

c. Hyperthermia

d. Hypertension

Inhibition of which of the following receptors would result in skeletal muscle paralysis?

a. Nicotinic type-N (NN) receptors

b. Nicotinic type-M (NM) receptors

c. Muscarinic-1 (M1) receptors

d. Muscarinic-2 (M2) receptors

Malignant hyperthermia is a potential adverse effect associated with which of the following drugs?

a. Succinylcholine

b. Pancuronium

c. Oxybutynin

d. Neostigmine

Which of the following drug classes may be clinically used to improve muscle weakness in individuals with myasthenia gravis?

a. Muscarinic agonists

b. Nicotinic type-N (NN) antagonists

c. Muscarinic antagonists

d. Indirect-acting cholinergic agonists

Which of the following drugs has addictive potential?

a. Neostigmine

b. Nicotine

c. Tubocurarine

d. Physostigmine

Which of the following drug classes may decrease hyperactivity of the bladder in a person with a spinal cord injury?

a. Muscarinic agonists

b. Nicotinic type-N (NN) antagonists

c. Muscarinic antagonists

d. Nicotinic type-M (NM) antagonists

Which of the following is an adverse effect associated with muscarinic agonists?

a. Constipation

b. Miosis

c. Bronchodilation

d. Hypertension

Which of the following drugs has clinical application for motion sickness?

a. Edrophonium

b. Nicotine

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