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Chapter 20: Opioid Analgesics and Antagonists

Activation of which of the following receptors is responsible for the strongest analgesic effect?

a. μ (mu) opioid receptor

b. δ (delta) opioid receptor

c. κ (kappa) opioid receptor

d. α (alpha) adrenergic receptor

Which of the following opioids is a strong (full) agonist at the μ (mu) opioid receptor?

a. Codeine

b. Oxycodone

c. Morphine

d. Buprenorphine

Which of the following opioid actions is not mediated by the central nervous system?

a. Decreased gastrointestinal motility

b. Miosis

c. Sedation

d. Respiratory depression

Which of the following drugs used to treat diarrhea would have the fewest central nervous system effects?

a. Codeine

b. Dextromethorphan

c. Loperamide

d. Morphine

Which of the following is not a sign or symptom of opioid withdrawal?

a. Muscle aches

b. Constipation

c. Chills

d. Fever

Which of the following is not a characteristic of a morphine or heroin overdose?

a. Pupillary dilation

b. Comatose state

c. Miosis

d. Respiratory depression

Which of the following drugs is used to quickly reverse an acute opioid overdose?

a. Naltrexone

b. Alvimopan

c. Naloxegol

d. Naloxone

Which of the following drugs most readily induces tolerance and dependence?

a. Codeine

b. Nalbuphine

c. Morphine

d. Buprenorphine

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