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Chapter 26: Antihyperlipidemic Drugs

Hypertriglyceridemia is most commonly associated with which of the following disorders?

a. Acute kidney failure

b. Atherosclerosis

c. Acute pancreatitis

d. Acute liver failure

Which of the following drugs is a monoclonal antibody?

a. Niacin

b. Lovastatin

c. Colestipol

d. Evolocumab

Which of the following drugs inhibits the enzyme proprotein convertase subtilisin/kexin type 9 (PCSK9)?

a. Alirocumab

b. Atorvastatin

c. Cholestyramine

d. Ezetimibe

Which of the following is responsible for removing cholesterol from the atherosclerotic plaques and returning it to the liver?

a. Low-density lipoproteins

b. Intermediate density lipoproteins

c. High-density lipoproteins

d. Chylomicrons

Which of the following drugs decreases plasma concentration of low-density lipoproteins (LDLs) and total cholesterol by inhibiting hepatic synthesis of cholesterol?

a. Evolocumab

b. Colestipol

c. Lovastatin

d. Niacin

Which of the following drugs decreases plasma cholesterol by binding cholesterol in the intestinal lumen and inhibiting its uptake into the body?

a. Cholestyramine

b. Ezetimibe

c. Lovastatin

d. Niacin

Which of the following drugs would be most effective at reducing hypertriglyceridemia?

a. Cholestyramine

b. Clofibrate

c. Ezetimibe

d. Fluvastatin

Which of the following drugs is associated with the highest potential incidence for myopathy and rhabdomyolysis?

a. Colesevelam

b. Evolocumab

c. Ezetimibe

d. Pravastatin

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