Since the publication of the second edition of Movement Disorders:
Neurologic Principles and Practice there have been major advances in
understanding the molecular basis and range of clinical expression of many
of the diseases that make up this spectrum of neurological disorders, hence
the need for this third edition. In this new volume we have retained an
organization of sections that is based principally on clinical patterns of
disease expression the same (phenotypic approach), but we have placed
greater emphasis on the molecular etiologies, where known (molecular genetic
approach). Future editions will likely emphasize this mechanistic approach
even more strongly as our knowledge of underlying causes continues to
advance.
As in the first two editions, we have
sought to present the material in a logical fashion beginning with Part I:
Introduction to Movement Disorders (Chapters 1–3), followed by Part
II: Neuroscientific Foundations (Chapters 4–8), and concluding with
Part III: Clinical Disorders (Chapters 9–49, further segregated to
address the major categories of movement disorders). We have added a new
chapter on “Assessing Disability in Movement Disorders: Quantitative
Techniques and Rating Scales” (Chapter 2), a new chapter on “Neuroprotective
Therapies for Parkinson's Disease” (Chapter 14), and a new
chapter on “Restless Legs Syndrome and Periodic Leg Movements of Sleep”
(Chapter 47). We consolidated some smaller chapters where warranted. A large
number of tables and figures are included that help present data more
succinctly and are useful teaching aids; unique to this third edition is a
new DVD with videos of representative patients with various movement
disorders.
We are deeply appreciative for the
support of our families and professional colleagues throughout the
preparation of this third edition, and we are grateful for the assistance of
the editorial and publishing staff of McGraw-Hill (especially Anne Sydor and
Christie Naglieri). Particular appreciation is extended to Katherine (Kate)
Tully of the University of Alabama at Birmingham (UAB) for her assistance
with many aspects of the organizational, editorial, and publication
processes that brought this third edition to fruition, and to Amy Amara, MD,
PhD, a Movement Disorders Fellow at UAB, who was very helpful with the
creation of the DVD with patient videos.
We
dedicate this third edition to the work and memory of our dear colleague,
William C. Koller, MD, PhD, who was a co-editor of the first two editions.
It is our hope that readers will find this third edition
of even greater usefulness than the first two.
Ray
L. Watts, MD
David G. Standaert, MD, PhD
Jose A.
Obeso, MD