Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content ++ 733.0 Osteoporosis733.00 Osteoporosis unspecified733.01 Senile osteoporosis733.02 Idiopathic osteoporosis733.03 Disuse osteoporosis733.09 Other osteoporosis ++ M81.0 Age-related osteoporosis without current pathological fractureM81.8 Other osteoporosis without current pathological fracture ++ 4A: Primary Prevention/Risk Reduction for Skeletal Demineralization4B: Impaired Posture4C: Impaired Muscle Performance4F: Impaired Joint Mobility, Motor Function, Muscle Performance, ROM and Reflex Integrity Association with Spinal Disorders4G: Impaired Joint Mobility, Muscle Performance, and ROM Associated With Fracture +++ Description ++ Deterioration of bone mass and density with a marked decrease in cortical thickness and cancellous bone trabeculae, leading to increased fragility, deformity and/or fractureOsteoporosis is initially categorized by etiology and skeletal localization then further divided into primary and secondary classificationsConsidered both a progressive and chronic disease with primary prevention tied to childhood bone health and reduced risk factors (skeletal and nonskeletal)Primary osteoporosisType 1: postmenopausal osteoporosisType 2: age-associated (senile) osteoporosisIdiopathic osteoporosis (juvenile, premenopausal women, middle-aged men)Secondary osteoporosis (identifiable cause of bone loss)Underlying disease, deficiency, or drug induced +++ Essentials of Diagnosis2-5 ++ The operational definition of osteoporosis by the World Health Organization (WHO) is bone density that falls 2.5 standard deviations (SDs) or more below the mean for a young healthy same sex adult; referred to as a T-score of -2.5Bone mineral density (BMD) measurements are related to both peak bone mass and bone lossBone densitometry: normal BMD within 1 SD of the mean; T-score at -1.0 and greaterBone densitometry: low BMD (referred to as osteopenia) occurs between 1 and 2.5 SDs below the mean; T-score between -1.0 and -2.5Increased fracture propensity is due to demineralization secondary to osteoporosis; often occurs at the spine, hips, pelvis, or wristAs a comorbid condition, low levels of serum 25-hydroxyvitamin D are notedAccurate patient and family medical histories and early recognition through physical examination may lead to improved therapeutic outcomes10-year risk for fracture can be measured through Fracture Risk Assessments (FRAX® score)Pharmacotherapy can be measured through changes in laboratory values +++ General Considerations2-5 ++ Osteoporosis is considered a major public health problem of the elderly, especially postmenopausal womenLifetime osteoporosis-related fracture will be experienced by 50% of all women and 25% of all men over age 50Persons with low BMD are at an increased risk for the development of osteoporosis; prevention is critical to reduce incidenceAccording to the National Osteoporosis Foundation (NOF), over 10 million Americans have osteoporosis and another 34 million have low BMD, and therefore at increased risks for the development of osteoporosis +++ Demographics2-5 ++ Osteoporosis is the cause of approximately 1.5 million fractures per year, with 80% occurring in women and 20% occurring in menRecovery to pre-fracture levels of activity and function are estimated to be only 33% of all ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.