Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content ++ ChondrosarcomaEwing (or Ewing’s) sarcomaOsteosarcoma ++ 170 Malignant neoplasm of bone and articular cartilage170.0 Malignant neoplasm of bones of skull and face except mandible170.1 Malignant neoplasm of mandible170.2 Malignant neoplasm of vertebral column excluding sacrum and coccyx170.3 Malignant neoplasm of ribs sternum and clavicle170.4 Malignant neoplasm of scapula and long bones of upper limb170.5 Malignant neoplasm of short bones of upper limb170.6 Malignant neoplasm of pelvic bones sacrum and coccyx170.7 Malignant neoplasm of long bones of lower limb170.8 Malignant neoplasm of short bones of lower limb170.9 Malignant neoplasm of bone and articular cartilage site unspecified ++ C40.00 Malignant neoplasm of scapula and long bones of unspecified upper limbC40.10 Malignant neoplasm of short bones of unspecified upper limbC40.20 Malignant neoplasm of long bones of unspecified lower limbC40.30 Malignant neoplasm of short bones of unspecified lower limbC41.0 Malignant neoplasm of bones of skull and faceC41.1 Malignant neoplasm of mandibleC41.2 Malignant neoplasm of vertebral columnC41.3 Malignant neoplasm of ribs, sternum and clavicleC41.4 Malignant neoplasm of pelvic bones, sacrum and coccyxC41.9 Malignant neoplasm of bone and articular cartilage, unspecified ++ 4E: Impaired Joint Mobility, Motor Function, Muscle Performance, and Range of Motion Associated With Localized Inflammation16B: Impaired Aerobic Capacity/Endurance Associated With Deconditioning2 +++ Description ++ Considered either osteoclastic or osteoblasticAbnormal growth of cells within the boneCan be either benign or malignant (cancerous)Often spreads to bone from cancerous tumors in other areasBreastKidneyLungProstateThyroid +++ Essentials of Diagnosis ++ Some benign tumors have no symptoms until fractureMalignant tumorsBone pain at site, worse at nightFracture from simple trauma or no trauma at allMass or swelling at site of tumorFracture through cortical bone +++ General Considerations ++ Gradual onset of signs and symptomsDistal femur accounts for more than 40% of cases, with proximal tibia, proximal humerus, and mid and proximal femur following in frequency3Clinical correlation4 +++ Demographics ++ 6th most common malignancy in childhood33rd most common malignancy among adolescents3Occurs at an earlier age in girls than boys, corresponding to growth spurt3Ewing sarcoma most common in toddlers and young Caucasian males +++ Signs and Symptoms ++ Bone pain: constant, not dependent on position or activityFracturesSwelling, localizedFever3Weight loss3Presence of massSpontaneous pain from nerve-root irritationMotor weaknessMuscle wastingLower or upper motor-neuron changesSensory changesHydrocephalusPapilledemaElevated intracranial pressureChemotherapy; side effects includeNauseaVomitingDiarrheaAlopeciaMouth soresConjunctivitisUlcersLeukopeniaAnemiaThrombocytopeniaHeadachesDizzinessMenstrual irregularitiesInfertilityPeripheral neuropathies +++ Functional Implications ++ Loss of independence with ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.