Tumor, brain

• 191.7 Malignant neoplasm of brain stem
• 191.8 Malignant neoplasm of other parts of brain
• 191.9 Malignant neoplasm of brain, unspecified
• 198.3 Secondary malignant neoplasm of brain and spinal cord
• 225.0 Benign neoplasm of brain
• 237.5 Neoplasm of uncertain behavior of brain and spinal cord
• 239.6 Neoplasm of unspecified nature of brain
• V10.85 Personal history of malignant neoplasm of brain
• V12.41 Personal history of benign neoplasm of the brain

• C71.7 Malignant neoplasm of brain stem
• C71.8 Malignant neoplasm of overlapping sites of brain
• C71.9 Malignant neoplasm of brain, unspecified
• C79.31 Secondary malignant neoplasm of brain
• D33.0 Benign neoplasm of brain, supratentorial
• D33.1 Benign neoplasm of brain, infratentorial
• D33.2 Benign neoplasm of brain, unspecified
• D43.0 Neoplasm of uncertain behavior of brain, supratentorial
• D43.1 Neoplasm of uncertain behavior of brain, infratentorial
• D43.2 Neoplasm of uncertain behavior of brain, unspecified
• D49.6 Neoplasm of unspecified behavior of brain
• H47.631 Disorders of visual cortex in (due to) neoplasm, right side of brain
• H47.632 Disorders of visual cortex in (due to) neoplasm, left side of brain
• Z85.841 Personal history of malignant neoplasm of brain
• Z86.011 Personal history of benign neoplasm of the brain

• 5C: Impaired motor function and sensory integrity associated with nonprogressive disorders of the central nervous system—congenital origin or acquired in infancy or childhood
• 5D: Impaired motor function and sensory integrity associated with nonprogressive disorders of the central nervous system—acquired in adolescence or adulthood
• 5E: Impaired motor function and sensory integrity associated with progressive disorders of the central nervous system
• 6B: Impaired aerobic capacity/endurance associated with deconditioning1

Description

• Neoplasm in the brain tissue of either primary or secondary origin
• Brain tumor types according to age and site

Essentials of Diagnosis

• Classic triad2
  • Morning headache
  • Vomiting
  • Papilledema
• Breast, lung, melanoma, and renal cell cancers are most likely to metastasize to brain tissue
• Tumor can occur in any part of the brain; symptoms help identify location of tumor prior to diagnostic imaging
• Confirmation is commonly done by stereotactic biopsy or craniotomy

General Considerations

• Secondary metastatic deposits are more common in adults than in children
• Frequency and location of pediatric brain tumors
  • Posterior fossa—most common frequency and location of pediatric brain tumors2
• AIDS, neurofibromatosis, and systemic cancers predispose the patient to development of a tumor in the nervous system
• Growth rates and invasiveness vary
  • Glioblastomas are highly malignant and invasive
  • Meningiomas are benign and slowly progressive

Demographics

• Approximately 20,000 people die annually in the United States from a malignant glioma
• Approximately 130,000 people who die with cancer have evidence of metastases to the brain
• In children, primary brain tumors constitute the most common solid tumor and represent 25% to 30% of childhood neoplasms2
• Medulloblastomas, spongioblastomas, optic nerve gliomas, and pinealomas occur most frequently before age 20
• Meningiomas and glioblastomas occur more frequently after age 50
• Glioblastomas occur ...