TY - CHAP M1 - Book, Section TI - Pharmacodynamics A1 - Jobst, Erin E. A1 - Panus, Peter C. A1 - Kruidering-Hall, Marieke PY - 2020 T2 - Pharmacology for the Physical Therapist, 2e AB - It is estimated that medications are involved in up to 80% of all treatments and impact every aspect of a patient’s life. As a result, physical therapists must recognize that drugs may alter a patient’s clinical presentation, which at times may require that physical therapy interventions be modified. Knowledge of drug classes and their mechanisms of actions is key to understanding patients’ responses to medications. The beneficial clinical effects of drugs occur within specific concentration ranges. These ranges are unique to the different pharmacologic classes of drugs and, for some drugs, unique to the specific individual. Concentrations below the effective range provide no therapeutic benefit, while concentrations above the range almost always result in adverse drug reactions (ADRs). As discussed in the Chapter 3, the goal of dosing regimens is to utilize knowledge of the therapeutic range for each drug to determine the frequency and dose for a specific person. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=1192812914 ER -