TY - CHAP M1 - Book, Section TI - Antipsychotic Agents and Lithium A1 - Jobst, Erin E. A1 - Panus, Peter C. A1 - Kruidering-Hall, Marieke PY - 2020 T2 - Pharmacology for the Physical Therapist, 2e AB - CASE STUDYM.M. is a 56-year-old man who was referred to rehabilitation by his physician after several falls and increasing balance problems as per his wife’s observation. The patient has a history of schizophrenia that has been well controlled with medication. Recent imaging and clinical diagnostic tests have ruled out any neurological or structural central nervous system (CNS) pathology. M.M. is currently taking pantoprazole (a proton pump inhibitor) and quetiapine. During the patient interview, M.M. reported that his prescribing practitioner increased his dose of quetiapine after a psychotic episode 2 months ago. Hesitantly, M.M. also reported several recent episodes of lightheadedness. M.M. states that he has begun to feel extremely stiff at times and has had a hard time moving. During the physical therapy examination, M.M. appeared to be in no acute physical distress. When moving from sitting to standing, M.M. stated that he became slightly lightheaded with the edges of his vision blurring. The therapist confirmed orthostatic hypotension during a sit-to-stand transfer with a fall in systolic and diastolic blood pressure of 24 and 18 mm Hg, respectively. Although M.M. had normal range of motion and strength in all extremities, he displayed some postural rigidity evident by resistance to passive stretch that was more severe in the lower extremities. The patient did not demonstrate a resting tremor. M.M.’s performance on the Mini-BESTest revealed moderate impairments in dynamic balance. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=1192816090 ER -