TY - CHAP M1 - Book, Section TI - Chapter 13. Clinical Manifestations of Parkinson's Disease A1 - Wilkinson, Jayne R. A1 - Weintraub, Daniel A1 - Stern, Matthew B. A2 - Watts, Ray L. A2 - Standaert, David G. A2 - Obeso, Jose A. PY - 2012 T2 - Movement Disorders, 3e AB - James Parkinson's original 1817 description of the “shaking palsy” remains a remarkably accurate account of the disease now bearing his name.1 Although the cardinal manifestations of Parkinson's disease (PD) are no different today, our understanding of the full array of parkinsonian signs and symptoms continues to grow. In addition to motor symptoms, the nonmotor symptoms of PD are now recognized as a significant source of disability.2 Given continuing advances in therapy, it is increasingly important that clinicians recognize PD in its earliest stages. Equally critical, PD must be distinguished from less common forms of parkinsonism because prognosis and treatment may differ. In this chapter, we discuss the motor and nonmotor clinical manifestations of PD, followed by a discussion of clinical signs that can distinguish PD from other parkinsonian syndromes. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=55793554 ER -