TY - CHAP M1 - Book, Section TI - Chapter 14. Neuroprotective Therapies for Parkinson's Disease A1 - Yacoubian, Talene A. A1 - Standaert, David G. A2 - Watts, Ray L. A2 - Standaert, David G. A2 - Obeso, Jose A. PY - 2012 T2 - Movement Disorders, 3e AB - Parkinson's disease (PD) is a relentlessly progressive disorder. The symptoms are usually mild at onset, most frequently a resting tremor of a hand, but worsen steadily over years to cause severe disability in most cases. Indeed, much evidence suggests that the onset of the neurodegenerative process precedes the appearance of clinical symptoms by as much as a decade, and that the neurodegenerative process is well established by the time the disease is clinically apparent. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=55793891 ER -