TY - CHAP M1 - Book, Section TI - Chapter 6. Functional Neurochemistry of the Basal Ganglia A1 - Nicholas, Anthony P. A1 - Standaert, David G. A2 - Watts, Ray L. A2 - Standaert, David G. A2 - Obeso, Jose A. Y1 - 2012 N1 - T2 - Movement Disorders, 3e AB - Progressive degeneration of neurons of the various nuclei of the basal ganglia leads to many clinical disorders manifesting in severe disabling motor, autonomic, and cognitive problems. The different nuclei of the basal ganglia, especially the striatum, are the sites of actions of diverse neurotransmitters and neuropeptides.1 Classic and modern neuroanatomical and neurochemical studies have enabled us to draw a working model of the circuits of the basal ganglia.2–4 Although very much simplified, these models have been valuable and have advanced our understanding of the molecular circuitries as well as the role played by the individual neurotransmitters and neuropeptides in the functions of the basal ganglia. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=55791634 ER -