TY - CHAP M1 - Book, Section TI - Chapter 21. Progressive Supranuclear Palsy A1 - Golbe, Lawrence I. A2 - Watts, Ray L. A2 - Standaert, David G. A2 - Obeso, Jose A. Y1 - 2012 N1 - T2 - Movement Disorders, 3e AB - The first clinicopathologic descriptions of progressive supranuclear palsy (PSP) to draw widespread attention were published in 1963 and 1964.1–3 The full-blown, typical case is at once unusually complex in its combination of motor and behavioral features and so distinctive that the diagnosis is unmistakable at a glance. Lack of objective diagnostic markers and poor response to treatment make PSP a challenge for the clinician and a trial for the patient and family. But recent progress in understanding its genetic, molecular, and cellular pathology offer hope that PSP will become more easily diagnosed and treated in the near future. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=55796283 ER -