TY - CHAP M1 - Book, Section TI - Thyroid Disease A1 - Esfandiari, Nazanene H. A1 - McPhee, Stephen J. A2 - Hammer, Gary D. A2 - McPhee, Stephen J. PY - 2019 T2 - Pathophysiology of Disease: An Introduction to Clinical Medicine, 8e AB - The thyroid gland synthesizes the hormones thyroxine (T4) (prohormone) and triiodothyronine (T3) (active hormone), iodine-containing amino acids that regulate the body’s metabolic rate. Adequate levels of thyroid hormone are necessary in infants for normal central nervous system (CNS) development, in children for normal skeletal growth and maturation, and in adults for the normal function of multiple organ systems. Thyroid dysfunction is one of the most common endocrine disorders encountered in clinical practice. Although abnormally high or low levels of thyroid hormones may be tolerated for long periods of time, there are usually symptoms and signs of overt thyroid dysfunction. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=1156659974 ER -