TY  - CHAP
M1  - Book, Section
TI  - Chapter 67. Diseases of Bones
A1  - Chandrasoma, Parakrama
A1  - Taylor, Clive R.
PY  - 1998
T2  - Concise Pathology, 3e
AB  - The  skeleton  is  composed  of  flat  bones  and  long  tubular  bones.  Flat  bones  such  as  the  skull,  sternum,  and  pelvic  bones  develop  from  fibrous  tissue  (through  intramembranous  ossification),  whereas  long  tubular  bones  increase  in  length  at  a  line  of  cartilage  present  near  the  growing  bone  ends  known  as  the  epiphysial  plate  or  growth  plate.  Anatomic  regions  of  long  bones  relate  to  the  growth  plate  and  include  the  epiphysis,  which  is  the  region  between  the  growth  plate  and  the  nearest  joint;  the  diaphysis,  which  is  the  shaft  region  of  the  bone  between  the  two  growth  plates;  and  the  metaphysis,  which  is  the  region  of  bone  adjacent  to  the  growth  plate  on  the  diaphysial  side.  The  metaphysis  is  the  area  where  new  bone  is  laid  down  during  growth,  and  in  children  it  represents  the  most  vascular  and  most  metabolically  active  region  of  bone.  For  this  reason,  the  metaphysial  region  is  the  area  most  susceptible  to  infections  and  neoplasm  formation  in  childhood.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessphysiotherapy.mhmedical.com/content.aspx?aid=193533
ER  -