TY - CHAP M1 - Book, Section TI - Chapter 22. Growth, Thyroid, and Gonadal Pharmacology A1 - Panus, Peter C. A1 - Jobst, Erin E. A1 - Masters, Susan B. A1 - Katzung, Bertram A1 - Tinsley, Suzanne L. A1 - Trevor, Anthony J. PY - 2009 T2 - Pharmacology for the Physical Therapist AB - The endocrine system integrates major organ systems with each other and with the nervous system. The endogenous ligands that the endocrine system uses to perform this integrative task are called hormones. Hormones are released from specialized cells, circulate in the blood, and regulate physiologic processes in one or more target organs. In many endocrine systems, several hormones act in series to regulate organ function. The release of one hormone in the series regulates the release of the next hormone. A series of this type provides multiple levels of regulation and integration and also provides the opportunity for negative feedback, in which the last hormone in the series can reduce the production of earlier hormones in the series and thereby regulate its own production (Figure 22–1). The endocrine system provides many useful therapeutic targets and many drugs either mimic or block the effects of naturally occurring hormones. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accessphysiotherapy.mhmedical.com/content.aspx?aid=6093102 ER -