RT Book, Section A1 Waxman, Stephen G. SR Print(0) ID 1137638254 T1 Vascular Supply of the Brain T2 Clinical Neuroanatomy, 28e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071847704 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=1137638254 RD 2024/04/19 AB The brain and spinal cord are critically dependent on an uninterrupted supply of oxygenated blood, and thus are dependent on unimpeded flow through the cerebral vessels. About 18% of the total blood volume in the body circulates in the brain, which accounts for about 2% of the body weight. The blood transports oxygen, nutrients, and other substances necessary for proper functioning of the brain and carries away metabolites. Loss of consciousness occurs in less than 15 seconds after blood flow to the brain has stopped, and irreparable damage to the brain tissue occurs within 5 minutes.