RT Book, Section A1 Burke-Doe, Annie A1 Lazaro, Rolando A2 Burke-Doe, Annie A2 Dutton, Mark SR Print(0) ID 1159272098 T1 Metabolic and Endocrine Systems T2 National Physical Therapy Examination and Board Review YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260010626 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=1159272098 RD 2024/04/18 AB The endocrine system is a collection of cells, tissues, glands, and organs that work together to produce and regulate signaling molecules called hormones. Hormones are released into the bloodstream where they bind to receptors, or in target cells, and function to regulate their activity to maintain homeostasis. The locations of selected endocrine glands and hormones released are shown in Figure 5–1. This system overlaps with the nervous system, and its responsibilities include the regulation of blood pressure, metabolism, growth and development, and reproduction. Hormone secretion itself is highly regulated by various mechanisms, including hormonal signals from the hypothalamus and the pituitary gland, and by positive and negative feedback from target cells.