RT Book, Section
A1 Jobst, Erin E.
A1 Panus, Peter C.
A1 Kruidering-Hall, Marieke
SR Print(0)
ID 1192812914
T1 Pharmacodynamics
T2 Pharmacology for the Physical Therapist, 2e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781259862229
LK accessphysiotherapy.mhmedical.com/content.aspx?aid=1192812914
RD 2024/04/18
AB It  is  estimated  that  medications  are  involved  in  up  to  80%  of  all  treatments  and  impact  every  aspect  of  a  patient’s  life.  As  a  result,  physical  therapists  must  recognize  that  drugs  may  alter  a  patient’s  clinical  presentation,  which  at  times  may  require  that  physical  therapy  interventions  be  modified.  Knowledge  of  drug  classes  and  their  mechanisms  of  actions  is  key  to  understanding  patients’  responses  to  medications.  The  beneficial  clinical  effects  of  drugs  occur  within  specific  concentration  ranges.  These  ranges  are  unique  to  the  different  pharmacologic  classes  of  drugs  and,  for  some  drugs,  unique  to  the  specific  individual.  Concentrations  below  the  effective  range  provide  no  therapeutic  benefit,  while  concentrations  above  the  range  almost  always  result  in  adverse  drug  reactions  (ADRs).  As  discussed  in  the  Chapter  3,  the  goal  of  dosing  regimens  is  to  utilize  knowledge  of  the  therapeutic  range  for  each  drug  to  determine  the  frequency  and  dose  for  a  specific  person.