RT Book, Section A1 Burke-Doe, Annie A2 Burke-Doe, Annie A2 Dutton, Mark SR Print(0) ID 1202329876 T1 Metabolic and Endocrine Systems T2 National Physical Therapy Examination and Board Review, 2nd Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781265019747 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=1202329876 RD 2024/09/14 AB The endocrine system is a collection of cells, tissues, glands, and organs that work together to produce and regulate signaling molecules called hormones.* Hormones are released into the bloodstream, bind to receptors or target cells, and function to regulate their activity to maintain homeostasis. The locations of selected endocrine glands and hormones released are shown in Figure 5–1. This system overlaps with the nervous system, and its responsibilities include regulating blood pressure, metabolism, growth and development, and reproduction. Hormone secretion is highly regulated by various mechanisms, including hormonal signals from the hypothalamus and the pituitary gland and positive and negative feedback from target cells.