RT Book, Section
A1 Nicholas, Anthony P.
A1 Standaert, David G.
A2 Watts, Ray L.
A2 Standaert, David G.
A2 Obeso, Jose A.
SR Print(0)
ID 55791634
T1 Chapter 6. Functional Neurochemistry of the Basal Ganglia
T2 Movement Disorders, 3e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-161312-5
LK accessphysiotherapy.mhmedical.com/content.aspx?aid=55791634
RD 2024/04/19
AB Progressive  degeneration  of  neurons  of  the  various  nuclei  of  the  basal  ganglia  leads  to  many  clinical  disorders  manifesting  in  severe  disabling  motor,  autonomic,  and  cognitive  problems.  The  different  nuclei  of  the  basal  ganglia,  especially  the  striatum,  are  the  sites  of  actions  of  diverse  neurotransmitters  and  neuropeptides.1  Classic  and  modern  neuroanatomical  and  neurochemical  studies  have  enabled  us  to  draw  a  working  model  of  the  circuits  of  the  basal  ganglia.2–4  Although  very  much  simplified,  these  models  have  been  valuable  and  have  advanced  our  understanding  of  the  molecular  circuitries  as  well  as  the  role  played  by  the  individual  neurotransmitters  and  neuropeptides  in  the  functions  of  the  basal  ganglia.