RT Book, Section A1 Kemp, Walter L. A1 Burns, Dennis K. A1 Brown, Travis G. SR Print(0) ID 57050729 T1 Chapter 3. Pathology of the Immune System T2 Pathology: The Big Picture YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-147748-2 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=57050729 RD 2024/03/28 AB Diseases of the immune system take many forms, including hypersensitivity reactions, autoimmune disorders, and immunodeficiency states. Hypersensitivity reactions occur as one of four types (types I–IV). Autoimmune diseases are the result of a failure in the immune system to recognize self-antigens, resulting in production of antibodies that react against normal components of cells. Most of the autoimmune diseases are associated with one or more specific antibodies, which can be identified by laboratory tests to aid in diagnosis. Immunodeficiency states can be hereditary or acquired. A major cause of acquired immunodeficiency is human immunodeficiency virus (HIV) infection. The concepts of immunity are also important in regard to transplantation efforts. This chapter will discuss hypersensitivity reactions, transplantation pathology, autoimmune diseases, amyloidosis, and both hereditary and acquired immunodeficiency.