RT Book, Section A1 Kemp, Walter L. A1 Burns, Dennis K. A1 Brown, Travis G. SR Print(0) ID 57051261 T1 Chapter 6. Genetic Disorders T2 Pathology: The Big Picture YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-147748-2 LK accessphysiotherapy.mhmedical.com/content.aspx?aid=57051261 RD 2024/11/05 AB There are three major types of mutations: (1) genome mutations, which involve loss or gain of an entire chromosome; (2) chromosomal mutations, which involve alterations in one or more chromosomes that are usually identifiable by karyotyping; and (3) gene mutations, which are partial or complete deletion of the gene or alteration of the base. Genome mutations usually result in death of the fetus, or death during infancy or early childhood.